It's been a couple of years, so you decide to see your primary-care physician for a physical.
You feel fine, but it's the responsible thing to do. You get your blood pressure measured and your blood drawn. Within a few days you'll get the lab report that will give you the readout on the amount of cholesterol and sugar in your blood. (This drill is so routine that you and your doctor don't even discuss the implications of a possible bad test result.) If you've entered your middle years, he'll probably ask if you want the lab to test your blood for PSA, a screening test that can tell you if you're at an elevated risk for prostate cancer.
Sometimes, pharmaceutical companies and their doctorly friends collectively make a bold move that shows their hand. Usually, this is in the form of indiscriminately and categorically broadening the eligible candidates for the suddenly lifesaving benefits of a pre-existing product. Recent changes in guidelines put forth by the American Heart Association and the American College of Cardiology aim to expand the recommendations of lipid-modifying statins to include those for whom there is a stated "10-year risk of 7.5 percent or more" of cardiac events, based on a calculator that now eliminates LDL targets.
I knew an eight-year old boy who traveled faster than the speed of light! He was highly intelligent and need only be shown something once, if at all, to quickly process it and move to the next activity. He bored easily and needed constant stimulation from new ideas and life experiences. It seemed as if he had the energy of the entire universe expanding inside him and needed to expend it into the world otherwise he might explode from the pressure!
His mother told me she was having problems coping with his high energy and was at her wits end. She said, “He doesn’t pay attention in school and I just can’t deal with him anymore.” She was going to put him on Ritalin.
When a new drug gets tested, the results of the trials should be published for the rest of the medical world -- except much of the time, negative or inconclusive findings go unreported, leaving doctors and researchers in the dark. In this TED Talk, Dr Ben Goldacre asserts that Publication Bias — the practice of selectively publishing trial results that serve an agenda — represents a “systematic flaw of the scientific basis of medicine,” He calls it “a cancer at the core of evidence-based medicine” and explains why these unreported instances of negative data are especially misleading and dangerous. Important TED talk as he exposes what is happening in medical research which undermines and contradicts everything modern medicine prides itself in.